STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAD1Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family. (595 aa)    
Predicted Functional Partners:
AGXT2
Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.906
GAD2
Glutamate decarboxylase 2; Catalyzes the production of GABA.
  
  
0.713
CALB1
Calbindin 1.
   
 
 0.696
CALB2
Calbindin 2.
   
 
 0.687
ABAT
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.685
TBR1
T-box brain transcription factor 1.
   
  
 0.679
SLC17A7
Solute carrier family 17 member 7.
   
 
 0.674
ALDH5A1
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.666
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
  
 0.636
DLX2
Distal-less homeobox 2.
   
  
 0.597
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.