STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NMUNeuromedin-U-25; Stimulates uterine smooth muscle contraction and causes selective vasoconstriction; Belongs to the NmU family. (170 aa)    
Predicted Functional Partners:
NMUR2
Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.998
NMUR1
Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.997
NMS
Neuromedin S.
     
0.950
NTSR1
Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.887
NTSR2
Neurotensin receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.862
NTS
Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
   
  
 0.719
RASGEF1A
RasGEF domain family member 1A.
      
 0.693
GHSR
Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.647
PMCH
Neuropeptide-glutamic acid-isoleucine; MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal.
      
 0.575
QRFP
Pyroglutamylated RFamide peptide.
      
 0.531
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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