STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC186Coiled-coil domain containing 186. (906 aa)    
Predicted Functional Partners:
NHLRC2
NHL repeat containing 2.
   
  
 0.858
VWA2
Von Willebrand factor A domain containing 2.
      
 0.826
AFAP1L2
Actin filament associated protein 1 like 2.
      
 0.810
CASC4
Cancer susceptibility 4.
      
 0.799
ARFIP2
ADP ribosylation factor interacting protein 2.
      
 0.794
VTI1A
Vesicle transport through interaction with t-SNAREs 1A.
      
 0.789
CCDC138
Coiled-coil domain containing 138.
      
 0.745
TMEM87A
Transmembrane protein 87A.
   
  
 0.741
VPS54
VPS54 subunit of GARP complex.
      
 0.692
EIPR1
EARP complex and GARP complex interacting protein 1.
      
 0.692
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.