node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP12A | ATP1B1 | ENSCAFP00000011046 | ENSCAFP00000022476 | Sodium/potassium-transporting ATPase subunit alpha. | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. | 0.832 |
ATP12A | ATP4A | ENSCAFP00000011046 | ENSCAFP00000055733 | Sodium/potassium-transporting ATPase subunit alpha. | Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | 0.901 |
ATP12A | ATP4B | ENSCAFP00000011046 | ENSCAFP00000009569 | Sodium/potassium-transporting ATPase subunit alpha. | Potassium-transporting ATPase subunit beta; Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity; Belongs to the X(+)/potassium ATPases subunit beta family. | 0.983 |
ATP12A | GAST | ENSCAFP00000011046 | ENSCAFP00000023420 | Sodium/potassium-transporting ATPase subunit alpha. | Big gastrin; Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine; Belongs to the gastrin/cholecystokinin family. | 0.407 |
ATP12A | LHPP | ENSCAFP00000011046 | ENSCAFP00000052127 | Sodium/potassium-transporting ATPase subunit alpha. | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase. | 0.937 |
ATP12A | LOC481394 | ENSCAFP00000011046 | ENSCAFP00000053513 | Sodium/potassium-transporting ATPase subunit alpha. | Uncharacterized protein. | 0.906 |
ATP12A | PPA1 | ENSCAFP00000011046 | ENSCAFP00000062051 | Sodium/potassium-transporting ATPase subunit alpha. | Uncharacterized protein. | 0.913 |
ATP1B1 | ATP12A | ENSCAFP00000022476 | ENSCAFP00000011046 | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. | Sodium/potassium-transporting ATPase subunit alpha. | 0.832 |
ATP1B1 | ATP4A | ENSCAFP00000022476 | ENSCAFP00000055733 | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. | Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | 0.701 |
ATP1B1 | ATP4B | ENSCAFP00000022476 | ENSCAFP00000009569 | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. | Potassium-transporting ATPase subunit beta; Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity; Belongs to the X(+)/potassium ATPases subunit beta family. | 0.540 |
ATP4A | ATP12A | ENSCAFP00000055733 | ENSCAFP00000011046 | Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Sodium/potassium-transporting ATPase subunit alpha. | 0.901 |
ATP4A | ATP1B1 | ENSCAFP00000055733 | ENSCAFP00000022476 | Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. | 0.701 |
ATP4A | ATP4B | ENSCAFP00000055733 | ENSCAFP00000009569 | Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Potassium-transporting ATPase subunit beta; Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity; Belongs to the X(+)/potassium ATPases subunit beta family. | 0.999 |
ATP4A | GAST | ENSCAFP00000055733 | ENSCAFP00000023420 | Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Big gastrin; Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine; Belongs to the gastrin/cholecystokinin family. | 0.852 |
ATP4A | HRH2 | ENSCAFP00000055733 | ENSCAFP00000053813 | Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Histamine H2 receptor; The H2 subclass of histamine receptors mediates gastric acid secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. | 0.824 |
ATP4A | LHPP | ENSCAFP00000055733 | ENSCAFP00000052127 | Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase. | 0.933 |
ATP4A | LOC481394 | ENSCAFP00000055733 | ENSCAFP00000053513 | Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Uncharacterized protein. | 0.905 |
ATP4A | LOC483842 | ENSCAFP00000055733 | ENSCAFP00000039860 | Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Uncharacterized protein. | 0.704 |
ATP4A | NIM1K | ENSCAFP00000055733 | ENSCAFP00000027408 | Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | NIM1 serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.688 |
ATP4A | PPA1 | ENSCAFP00000055733 | ENSCAFP00000062051 | Potassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. | Uncharacterized protein. | 0.913 |