STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D20TBC1 domain family member 20. (403 aa)    
Predicted Functional Partners:
RAB18
RAB18, member RAS oncogene family.
      
 0.891
RAB3GAP2
RAB3 GTPase activating non-catalytic protein subunit 2.
      
 0.889
F6XUK4_CANLF
Uncharacterized protein.
    
 0.881
RAB1A
Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...]
    
 0.881
RAB1B
RAB1B, member RAS oncogene family.
   
 
 0.861
RAB3GAP1
RAB3 GTPase activating protein catalytic subunit 1.
   
  
 0.847
TBC1D7
TBC1 domain family member 7.
   
  
 0.717
DENND1B
DENN domain containing 1B.
      
 0.704
TBC1D21
TBC1 domain family member 21.
   
  
 0.699
TBC1D10C
TBC1 domain family member 10C.
   
  
 0.695
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: medium (56%) [HD]