LOC100049001 protein (Canis lupus familiaris)

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LOC100049001

Tryptase; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily. (494 aa)

Predicted Functional Partners:

KLK10

0.540

KLK6

0.535

J9NXN6_CANLF

0.532

ENSCAFP00000047054

0.508

TBC1D24

0.486

CMA1

0.466

KRBA1

0.460

TMPRSS4

0.442

ACE2

0.428

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE2	CMA1	ENSCAFP00000041771	ENSCAFP00000018316	Angiotensin-converting enzyme.	Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.	0.986
ACE2	ENSCAFP00000047054	ENSCAFP00000041771	ENSCAFP00000047054	Angiotensin-converting enzyme.	Peptidase S1 domain-containing protein.	0.656
ACE2	LOC100049001	ENSCAFP00000041771	ENSCAFP00000046459	Angiotensin-converting enzyme.	Tryptase; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	0.428
ACE2	TMPRSS4	ENSCAFP00000041771	ENSCAFP00000058627	Angiotensin-converting enzyme.	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	0.683
CMA1	ACE2	ENSCAFP00000018316	ENSCAFP00000041771	Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.	Angiotensin-converting enzyme.	0.986
CMA1	J9NXN6_CANLF	ENSCAFP00000018316	ENSCAFP00000038049	Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.573
CMA1	LOC100049001	ENSCAFP00000018316	ENSCAFP00000046459	Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.	Tryptase; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	0.466
CMA1	TMPRSS4	ENSCAFP00000018316	ENSCAFP00000058627	Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	0.422
ENSCAFP00000047054	ACE2	ENSCAFP00000047054	ENSCAFP00000041771	Peptidase S1 domain-containing protein.	Angiotensin-converting enzyme.	0.656
ENSCAFP00000047054	LOC100049001	ENSCAFP00000047054	ENSCAFP00000046459	Peptidase S1 domain-containing protein.	Tryptase; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	0.508
J9NXN6_CANLF	CMA1	ENSCAFP00000038049	ENSCAFP00000018316	Uncharacterized protein; Belongs to the peptidase S1 family.	Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.	0.573
J9NXN6_CANLF	LOC100049001	ENSCAFP00000038049	ENSCAFP00000046459	Uncharacterized protein; Belongs to the peptidase S1 family.	Tryptase; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	0.532
KLK10	KLK6	ENSCAFP00000039593	ENSCAFP00000033419	Kallikrein related peptidase 10; Belongs to the peptidase S1 family.	Kallikrein related peptidase 6; Belongs to the peptidase S1 family.	0.421
KLK10	LOC100049001	ENSCAFP00000039593	ENSCAFP00000046459	Kallikrein related peptidase 10; Belongs to the peptidase S1 family.	Tryptase; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	0.540
KLK6	KLK10	ENSCAFP00000033419	ENSCAFP00000039593	Kallikrein related peptidase 6; Belongs to the peptidase S1 family.	Kallikrein related peptidase 10; Belongs to the peptidase S1 family.	0.421
KLK6	LOC100049001	ENSCAFP00000033419	ENSCAFP00000046459	Kallikrein related peptidase 6; Belongs to the peptidase S1 family.	Tryptase; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	0.535
KRBA1	LOC100049001	ENSCAFP00000042940	ENSCAFP00000046459	KRAB-A domain containing 1.	Tryptase; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	0.460
LOC100049001	ACE2	ENSCAFP00000046459	ENSCAFP00000041771	Tryptase; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	Angiotensin-converting enzyme.	0.428
LOC100049001	CMA1	ENSCAFP00000046459	ENSCAFP00000018316	Tryptase; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.	0.466
LOC100049001	ENSCAFP00000047054	ENSCAFP00000046459	ENSCAFP00000047054	Tryptase; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	Peptidase S1 domain-containing protein.	0.508

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