node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CRB3 | EZR | ENSCAFP00000044539 | ENSCAFP00000000937 | Crumbs cell polarity complex component 3. | FERM domain-containing protein. | 0.425 |
CRB3 | PODXL | ENSCAFP00000044539 | ENSCAFP00000002008 | Crumbs cell polarity complex component 3. | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...] | 0.564 |
CRB3 | SET | ENSCAFP00000044539 | ENSCAFP00000038919 | Crumbs cell polarity complex component 3. | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. | 0.414 |
EZR | CRB3 | ENSCAFP00000000937 | ENSCAFP00000044539 | FERM domain-containing protein. | Crumbs cell polarity complex component 3. | 0.425 |
EZR | PODXL | ENSCAFP00000000937 | ENSCAFP00000002008 | FERM domain-containing protein. | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...] | 0.674 |
EZR | SLC9A3R1 | ENSCAFP00000000937 | ENSCAFP00000006867 | FERM domain-containing protein. | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. | 0.999 |
EZR | SLC9A3R2 | ENSCAFP00000000937 | ENSCAFP00000061476 | FERM domain-containing protein. | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. | 0.691 |
MAG | PODXL | ENSCAFP00000033164 | ENSCAFP00000002008 | Myelin associated glycoprotein. | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...] | 0.552 |
NPHS1 | NPHS2 | ENSCAFP00000010092 | ENSCAFP00000020384 | NPHS1 adhesion molecule, nephrin. | NPHS2 stomatin family member, podocin. | 0.917 |
NPHS1 | PODXL | ENSCAFP00000010092 | ENSCAFP00000002008 | NPHS1 adhesion molecule, nephrin. | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...] | 0.611 |
NPHS1 | WT1 | ENSCAFP00000010092 | ENSCAFP00000058748 | NPHS1 adhesion molecule, nephrin. | WT1 transcription factor. | 0.944 |
NPHS2 | NPHS1 | ENSCAFP00000020384 | ENSCAFP00000010092 | NPHS2 stomatin family member, podocin. | NPHS1 adhesion molecule, nephrin. | 0.917 |
NPHS2 | PODXL | ENSCAFP00000020384 | ENSCAFP00000002008 | NPHS2 stomatin family member, podocin. | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...] | 0.740 |
NPHS2 | WT1 | ENSCAFP00000020384 | ENSCAFP00000058748 | NPHS2 stomatin family member, podocin. | WT1 transcription factor. | 0.988 |
PODXL | CRB3 | ENSCAFP00000002008 | ENSCAFP00000044539 | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...] | Crumbs cell polarity complex component 3. | 0.564 |
PODXL | EZR | ENSCAFP00000002008 | ENSCAFP00000000937 | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...] | FERM domain-containing protein. | 0.674 |
PODXL | MAG | ENSCAFP00000002008 | ENSCAFP00000033164 | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...] | Myelin associated glycoprotein. | 0.552 |
PODXL | NPHS1 | ENSCAFP00000002008 | ENSCAFP00000010092 | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...] | NPHS1 adhesion molecule, nephrin. | 0.611 |
PODXL | NPHS2 | ENSCAFP00000002008 | ENSCAFP00000020384 | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...] | NPHS2 stomatin family member, podocin. | 0.740 |
PODXL | SELL | ENSCAFP00000002008 | ENSCAFP00000022356 | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...] | L-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. | 0.589 |