STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZNF236Zinc finger protein 236. (1836 aa)    
Predicted Functional Partners:
CAPN15
Calpain 15; Belongs to the peptidase C2 family.
    
 
 0.769
TFB2M
rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
    
 
 0.758
MAMLD1
Mastermind like domain containing 1.
    
 
 0.750
DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
     
 0.711
FOXP2
Forkhead box P2.
    
 
 0.667
CA8
Carbonic anhydrase 8; Belongs to the alpha-carbonic anhydrase family.
      
 0.665
ERCC6
ERCC excision repair 6, chromatin remodeling factor.
   
   0.634
SPIB
Myosin binding protein C, fast type.
    
 
 0.611
DEPDC1
DEP domain containing 1.
      
 0.533
TRDN
Triadin; Contributes to the regulation of lumenal Ca2+ release via the sarcoplasmic reticulum calcium release channels RYR1 and RYR2, a key step in triggering skeletal and heart muscle contraction. Required for normal organization of the triad junction, where T-tubules and the sarcoplasmic reticulum terminal cisternae are in close contact. Required for normal skeletal muscle strength. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.
    
 
 0.530
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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