STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMX3Thioredoxin related transmembrane protein 3. (453 aa)    
Predicted Functional Partners:
EMC6
ER membrane protein complex subunit 6.
      
 0.708
GSR
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
   
 
 0.632
TMX4
Thioredoxin related transmembrane protein 4.
   
 
 0.601
TMX2
Thioredoxin related transmembrane protein 2.
   
 
 0.581
UNC50
Unc-50 inner nuclear membrane RNA binding protein.
   
  
 0.566
ENSCAFP00000043906
J domain-containing protein.
    
 
 0.559
GLRX
Glutaredoxin.
  
 
 0.541
HELZ
Helicase with zinc finger.
   
  
 0.527
MCUB
Mitochondrial calcium uniporter dominant negative beta subunit.
      
 0.520
TXNDC15
Thioredoxin domain containing 15.
   
  
 0.518
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.