CDH7 protein (Canis lupus familiaris) - STRING interaction network

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CDH7

Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)

Predicted Functional Partners:

CTNNB1

0.962

JUP

0.949

CDH12

0.943

LOC102154778

0.943

CTNNA1

0.943

CDH1

0.915

CDH2

0.913

LOC489647

0.913

CDH3

0.913

CDH13

0.913

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH1	CDH12	ENSCAFP00000030112	ENSCAFP00000028088	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.	Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.	0.900
CDH1	CDH13	ENSCAFP00000030112	ENSCAFP00000060570	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.	Cadherin 13.	0.903
CDH1	CDH2	ENSCAFP00000030112	ENSCAFP00000026768	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.927
CDH1	CDH3	ENSCAFP00000030112	ENSCAFP00000055419	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.	Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins.	0.904
CDH1	CDH7	ENSCAFP00000030112	ENSCAFP00000000060	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.	Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins.	0.915
CDH1	CTNNA1	ENSCAFP00000030112	ENSCAFP00000054655	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.	Catenin alpha 1.	0.979
CDH1	CTNNB1	ENSCAFP00000030112	ENSCAFP00000007783	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	0.999
CDH1	JUP	ENSCAFP00000030112	ENSCAFP00000023403	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.	Uncharacterized protein.	0.994
CDH1	LOC102154778	ENSCAFP00000030112	ENSCAFP00000038187	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.	Uncharacterized protein.	0.963
CDH1	LOC489647	ENSCAFP00000030112	ENSCAFP00000030107	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.	Uncharacterized protein.	0.904
CDH12	CDH1	ENSCAFP00000028088	ENSCAFP00000030112	Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.	0.900
CDH12	CDH13	ENSCAFP00000028088	ENSCAFP00000060570	Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 13.	0.912
CDH12	CDH2	ENSCAFP00000028088	ENSCAFP00000026768	Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.917
CDH12	CDH3	ENSCAFP00000028088	ENSCAFP00000055419	Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins.	0.900
CDH12	CDH7	ENSCAFP00000028088	ENSCAFP00000000060	Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins.	0.943
CDH12	CTNNA1	ENSCAFP00000028088	ENSCAFP00000054655	Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.	Catenin alpha 1.	0.941
CDH12	CTNNB1	ENSCAFP00000028088	ENSCAFP00000007783	Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	0.959
CDH12	JUP	ENSCAFP00000028088	ENSCAFP00000023403	Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.937
CDH12	LOC102154778	ENSCAFP00000028088	ENSCAFP00000038187	Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.939
CDH12	LOC489647	ENSCAFP00000028088	ENSCAFP00000030107	Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.908