STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SERPINB13Serpin family B member 13; Belongs to the serpin family. (433 aa)    
Predicted Functional Partners:
CTSG
Granzyme B; Belongs to the peptidase S1 family.
   
 0.827
SERPINB10
Serpin family B member 10; Belongs to the serpin family.
     
  0.769
LOC102156614
Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family.
   
 0.766
CTSL3
Uncharacterized protein; Belongs to the peptidase C1 family.
    
 0.717
SERPING1
Serpin family G member 1; Belongs to the serpin family.
  
  0.647
PACSIN3
Protein kinase C and casein kinase substrate in neurons 3.
      
 0.591
SERPINB6
Serpin family B member 6; Belongs to the serpin family.
     
  0.591
SERPINB9
Serpin family B member 9; Belongs to the serpin family.
     
  0.591
PTPN3
Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton.
      
 0.534
SERPINB8
Serpin family B member 8; Belongs to the serpin family.
     
  0.532
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.