STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPINB12Serpin family B member 12; Belongs to the serpin family. (423 aa)    
Predicted Functional Partners:
KPRP
Keratinocyte proline rich protein.
   
 0.796
CASP14
Caspase 14; Belongs to the peptidase C14A family.
   
 
 0.652
LOC610677
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 
 0.652
SERPING1
Serpin family G member 1; Belongs to the serpin family.
  
  0.647
TGM3
Transglutaminase 3.
   
 
 0.629
KLK13
Kallikrein related peptidase 13; Belongs to the peptidase S1 family.
   
 0.625
ENSCAFP00000051572
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
    
   0.619
CSTA
Cystatin A; Belongs to the cystatin family.
    
 
 0.598
CDSN
Corneodesmosin.
   
  
 0.567
SBSN
Uncharacterized protein.
   
  
 0.558
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.