STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E2R033_CANLFSERPIN domain-containing protein; Belongs to the serpin family. (389 aa)    
Predicted Functional Partners:
CTSG
Granzyme B; Belongs to the peptidase S1 family.
   
 0.920
LOC488303
Histone H2B type 1-K.
      
 0.650
KAT14
Lysine acetyltransferase 14.
    
 
 0.639
LOC488290
Histone H2B; Belongs to the histone H2B family.
      
 0.565
ZNF34
Zinc finger protein 34.
    
 
 0.520
ZNF250
Zinc finger protein 250.
    
 
 0.520
KRT32
Keratin 32; Belongs to the intermediate filament family.
   
  
 0.488
TRAF3IP3
TRAF3 interacting protein 3.
   
 
 0.486
CRNN
Cornulin.
   
  
 0.485
XRCC3
DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.
      
 0.485
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.