NMBR protein (Canis lupus familiaris) - STRING interaction network

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Score

NMBR

Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (390 aa)

Predicted Functional Partners:

NMB

0.984

GRP

0.920

GRPR

0.908

BRS3

0.907

NTS

0.633

KCNK18

0.621

NMS

0.607

BAG2

0.603

PROK2

0.582

EDN1

0.556

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAG2	GRPR	ENSCAFP00000040404	ENSCAFP00000018079	BCL2 associated athanogene 2.	Gastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family.	0.438
BAG2	NMBR	ENSCAFP00000040404	ENSCAFP00000000410	BCL2 associated athanogene 2.	Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.603
BRS3	EDN1	ENSCAFP00000027963	ENSCAFP00000014389	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.571
BRS3	GRP	ENSCAFP00000027963	ENSCAFP00000000137	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	0.949
BRS3	GRPR	ENSCAFP00000027963	ENSCAFP00000018079	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Gastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family.	0.910
BRS3	NMB	ENSCAFP00000027963	ENSCAFP00000036677	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Neuromedin B.	0.966
BRS3	NMBR	ENSCAFP00000027963	ENSCAFP00000000410	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.907
BRS3	NMS	ENSCAFP00000027963	ENSCAFP00000030920	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Neuromedin S.	0.531
BRS3	NTS	ENSCAFP00000027963	ENSCAFP00000008959	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.	0.715
BRS3	PROK2	ENSCAFP00000027963	ENSCAFP00000047793	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	Prokineticin 2.	0.556
EDN1	BRS3	ENSCAFP00000014389	ENSCAFP00000027963	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	0.571
EDN1	GRP	ENSCAFP00000014389	ENSCAFP00000000137	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	0.492
EDN1	GRPR	ENSCAFP00000014389	ENSCAFP00000018079	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Gastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family.	0.593
EDN1	NMB	ENSCAFP00000014389	ENSCAFP00000036677	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Neuromedin B.	0.491
EDN1	NMBR	ENSCAFP00000014389	ENSCAFP00000000410	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.556
EDN1	NMS	ENSCAFP00000014389	ENSCAFP00000030920	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Neuromedin S.	0.400
EDN1	NTS	ENSCAFP00000014389	ENSCAFP00000008959	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.	0.607
EDN1	PROK2	ENSCAFP00000014389	ENSCAFP00000047793	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Prokineticin 2.	0.431
GRP	BRS3	ENSCAFP00000000137	ENSCAFP00000027963	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	0.949
GRP	EDN1	ENSCAFP00000000137	ENSCAFP00000014389	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.492