STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL22Interleukin 22. (179 aa)    
Predicted Functional Partners:
IL10RB
Interleukin 10 receptor subunit beta.
    
 0.986
IL22RA2
Interleukin 22 receptor subunit alpha 2.
   
 0.971
IL23R
Interleukin 23 receptor.
   
 
 0.950
IL17A
Interleukin 17A.
  
  
 0.928
IL26
Interleukin 26.
   
  
 0.910
IL22RA1
Interleukin 22 receptor subunit alpha 1.
   
 
 0.902
IL17F
Interleukin 17F.
   
  
 0.896
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.
   
  
 0.878
CCR6
C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.874
IL20RA
Interleukin 20 receptor subunit alpha.
     
 0.873
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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