STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZDHHC14Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (487 aa)    
Predicted Functional Partners:
MCF2L2
MCF.2 cell line derived transforming sequence-like 2.
   
  
 0.711
RBL1
RB transcriptional corepressor like 1.
   
  
 0.627
LRCH3
Leucine rich repeats and calponin homology domain containing 3.
      
 0.539
ZDHHC13
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
      
0.520
PMEPA1
Prostate transmembrane protein, androgen induced 1.
    
 
 0.518
SNX1
Sorting nexin 1.
   
 
 0.503
ZBTB20
Zinc finger and BTB domain containing 20.
   
 
 0.502
PPP1CC
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density- asso [...]
   
 
 0.495
MPDZ
Multiple PDZ domain crumbs cell polarity complex component.
      
 0.495
CSNK2A1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 
 0.494
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.