STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM74Transmembrane protein 74. (305 aa)    
Predicted Functional Partners:
CDADC1
Cytidine and dCMP deaminase domain containing 1.
      
 0.800
WDR20
WD repeat domain 20.
      
 0.715
PAK1IP1
PAK1 interacting protein 1.
      
 0.677
DCAF13
DDB1 and CUL4 associated factor 13.
      
 0.671
RAB3GAP2
RAB3 GTPase activating non-catalytic protein subunit 2.
      
 0.662
ATG9B
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
    
 
 0.657
GCM2
Glial cells missing transcription factor 2.
      
 0.646
RCBTB1
RCC1 and BTB domain containing protein 1.
      
 0.646
DRAM1
DNA damage regulated autophagy modulator 1.
      
 0.613
AEBP1
AE binding protein 1.
      
 0.607
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.