STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM74Transmembrane protein 74. (305 aa)    
Predicted Functional Partners:
CDADC1
Cytidine and dCMP deaminase domain containing 1.
      
 0.810
TM4SF5
Transmembrane 4 L six family member 5.
      
 0.810
RNF103
Ring finger protein 103.
      
 0.698
ZFYVE28
Zinc finger FYVE-type containing 28.
      
 0.688
RCBTB1
RCC1 and BTB domain containing protein 1.
      
 0.687
SNAP47
Synaptosome associated protein 47.
      
 0.664
OTOGL
Otogelin like.
      
 0.602
FNDC3A
Fibronectin type III domain containing 3A.
      
 0.598
SETDB2
SET domain bifurcated histone lysine methyltransferase 2.
      
 0.598
RCBTB2
RCC1 and BTB domain containing protein 2.
      
 0.596
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.