STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LYRM7LYR motif containing 7; Belongs to the complex I LYR family. (104 aa)    
Predicted Functional Partners:
UQCRFS1
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
   
 0.986
ISCU
Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
   
 0.627
NFS1
Aminotran_5 domain-containing protein.
   
 
 0.614
BATF2
Basic leucine zipper ATF-like transcription factor 2.
    
 
 0.610
POLR2D
RNA polymerase II subunit D.
   
  
 0.609
RECQL5
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
  
 0.604
MRPL46
Mitochondrial ribosomal protein L46.
   
 
 0.604
POLR2G
RNA polymerase II subunit G.
   
  
 0.600
MRPL27
Mitochondrial ribosomal protein L27.
   
 
 0.598
FNDC4
Fibronectin type III domain containing 4.
      
 0.597
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.