STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTNL2Butyrophilin like 2. (505 aa)    
Predicted Functional Partners:
BRD2
Bromodomain-containing protein 2; Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly (By similarity). May play a role in spermatogenesis or folliculogenesis (By similarity).
    
 
 0.728
H2AC1
Histone H2A; Belongs to the histone H2A family.
    
 
 0.634
NOTCH4
Notch receptor 4.
    
 0.620
RPS15A
Uncharacterized protein; Belongs to the universal ribosomal protein uS8 family.
    
 
 0.612
TRIM39
Tripartite motif containing 39.
      
 0.611
TAP1
Uncharacterized protein.
   
 
 0.606
COL11A2
Collagen type XI alpha 2 chain.
    
 
 0.603
ANXA11
Annexin.
    
 
 0.569
RNF186
Ring finger protein 186.
    
 
 0.535
RPS27
40S ribosomal protein S27.
    
 
 0.534
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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