DLA-DQA1 protein (Canis lupus familiaris) - STRING interaction network

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Score

DLA-DQA1

Ig-like domain-containing protein; Belongs to the MHC class II family. (344 aa)

Predicted Functional Partners:

F1PSQ5_CANLF

0.970

CD74

0.959

HLA-DQB2

0.932

HLA-DQB1

0.920

E2R820_CANLF

0.853

DLA-12

0.833

DLA-79

0.828

HCRT

0.724

DLA-DRA

0.723

CD4

0.682

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD4	DLA-DQA1	ENSCAFP00000063394	ENSCAFP00000001164	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.682
CD4	DLA-DRA	ENSCAFP00000063394	ENSCAFP00000045482	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.984
CD4	E2R820_CANLF	ENSCAFP00000063394	ENSCAFP00000034736	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	DUF1968 domain-containing protein.	0.599
CD4	F1PSQ5_CANLF	ENSCAFP00000063394	ENSCAFP00000001282	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Uncharacterized protein.	0.735
CD4	HLA-DQB1	ENSCAFP00000063394	ENSCAFP00000001171	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Major histocompatibility complex, class II, DQ beta 2.	0.987
CD4	HLA-DQB2	ENSCAFP00000063394	ENSCAFP00000001156	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Major histocompatibility complex, class II, DQ beta 1.	0.971
CD74	DLA-DQA1	ENSCAFP00000045678	ENSCAFP00000001164	CD74 molecule.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.959
CD74	DLA-DRA	ENSCAFP00000045678	ENSCAFP00000045482	CD74 molecule.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.987
CD74	F1PSQ5_CANLF	ENSCAFP00000045678	ENSCAFP00000001282	CD74 molecule.	Uncharacterized protein.	0.933
CD74	HLA-DQB1	ENSCAFP00000045678	ENSCAFP00000001171	CD74 molecule.	Major histocompatibility complex, class II, DQ beta 2.	0.933
CD74	HLA-DQB2	ENSCAFP00000045678	ENSCAFP00000001156	CD74 molecule.	Major histocompatibility complex, class II, DQ beta 1.	0.903
DLA-12	DLA-79	ENSCAFP00000031410	ENSCAFP00000065183	Ig-like domain-containing protein; Belongs to the MHC class I family.	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.564
DLA-12	DLA-DQA1	ENSCAFP00000031410	ENSCAFP00000001164	Ig-like domain-containing protein; Belongs to the MHC class I family.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.833
DLA-12	E2R820_CANLF	ENSCAFP00000031410	ENSCAFP00000034736	Ig-like domain-containing protein; Belongs to the MHC class I family.	DUF1968 domain-containing protein.	0.558
DLA-79	DLA-12	ENSCAFP00000065183	ENSCAFP00000031410	Ig-like domain-containing protein; Belongs to the MHC class I family.	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.564
DLA-79	DLA-DQA1	ENSCAFP00000065183	ENSCAFP00000001164	Ig-like domain-containing protein; Belongs to the MHC class I family.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.828
DLA-79	DLA-DRA	ENSCAFP00000065183	ENSCAFP00000045482	Ig-like domain-containing protein; Belongs to the MHC class I family.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.828
DLA-79	E2R820_CANLF	ENSCAFP00000065183	ENSCAFP00000034736	Ig-like domain-containing protein; Belongs to the MHC class I family.	DUF1968 domain-containing protein.	0.843
DLA-DQA1	CD4	ENSCAFP00000001164	ENSCAFP00000063394	Ig-like domain-containing protein; Belongs to the MHC class II family.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.682
DLA-DQA1	CD74	ENSCAFP00000001164	ENSCAFP00000045678	Ig-like domain-containing protein; Belongs to the MHC class II family.	CD74 molecule.	0.959