TAP1 protein (Canis lupus familiaris) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

TAP1

Uncharacterized protein. (864 aa)

Predicted Functional Partners:

TAPBP

0.996

PSMB9

0.978

PDIA3

0.929

CALR

0.924

PSMB7

0.820

B2M

0.793

PSMB5

0.754

DLA-DOA

0.745

NLRC5

0.743

IRF1

0.730

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B2M	CALR	ENSCAFP00000047956	ENSCAFP00000025174	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Plays a major role in Ca2(+) storage in pancreatic cells.	0.731
B2M	DLA-DOA	ENSCAFP00000047956	ENSCAFP00000001280	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	MHC class II antigen DO alpha; Belongs to the MHC class II family.	0.569
B2M	PDIA3	ENSCAFP00000047956	ENSCAFP00000019653	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Protein disulfide-isomerase.	0.540
B2M	PSMB9	ENSCAFP00000047956	ENSCAFP00000038071	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Proteasome subunit beta.	0.505
B2M	TAP1	ENSCAFP00000047956	ENSCAFP00000064521	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Uncharacterized protein.	0.793
B2M	TAPBP	ENSCAFP00000047956	ENSCAFP00000001381	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Tapasin; Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).	0.811
CALR	B2M	ENSCAFP00000025174	ENSCAFP00000047956	Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Plays a major role in Ca2(+) storage in pancreatic cells.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.731
CALR	PDIA3	ENSCAFP00000025174	ENSCAFP00000019653	Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Plays a major role in Ca2(+) storage in pancreatic cells.	Protein disulfide-isomerase.	0.998
CALR	TAP1	ENSCAFP00000025174	ENSCAFP00000064521	Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Plays a major role in Ca2(+) storage in pancreatic cells.	Uncharacterized protein.	0.924
CALR	TAPBP	ENSCAFP00000025174	ENSCAFP00000001381	Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Plays a major role in Ca2(+) storage in pancreatic cells.	Tapasin; Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).	0.999
DLA-DOA	B2M	ENSCAFP00000001280	ENSCAFP00000047956	MHC class II antigen DO alpha; Belongs to the MHC class II family.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.569
DLA-DOA	TAP1	ENSCAFP00000001280	ENSCAFP00000064521	MHC class II antigen DO alpha; Belongs to the MHC class II family.	Uncharacterized protein.	0.745
IRF1	NLRC5	ENSCAFP00000001223	ENSCAFP00000046691	Interferon regulatory factor 1.	NLR family CARD domain containing 5.	0.668
IRF1	PSMB5	ENSCAFP00000001223	ENSCAFP00000016630	Interferon regulatory factor 1.	Proteasome subunit beta.	0.450
IRF1	PSMB9	ENSCAFP00000001223	ENSCAFP00000038071	Interferon regulatory factor 1.	Proteasome subunit beta.	0.594
IRF1	TAP1	ENSCAFP00000001223	ENSCAFP00000064521	Interferon regulatory factor 1.	Uncharacterized protein.	0.730
IRF1	TAPBP	ENSCAFP00000001223	ENSCAFP00000001381	Interferon regulatory factor 1.	Tapasin; Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).	0.504
NLRC5	IRF1	ENSCAFP00000046691	ENSCAFP00000001223	NLR family CARD domain containing 5.	Interferon regulatory factor 1.	0.668
NLRC5	PSMB9	ENSCAFP00000046691	ENSCAFP00000038071	NLR family CARD domain containing 5.	Proteasome subunit beta.	0.666
NLRC5	TAP1	ENSCAFP00000046691	ENSCAFP00000064521	NLR family CARD domain containing 5.	Uncharacterized protein.	0.743