STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDLIM4PDZ and LIM domain 4. (331 aa)    
Predicted Functional Partners:
PRSS23
Serine protease; Belongs to the peptidase S1B family.
   
  
 0.569
SH2B2
SH2B adaptor protein 2.
   
 
 0.568
NUDT14
Nudix hydrolase 14.
      
 0.561
FAM214B
Family with sequence similarity 214 member B.
      
 0.558
LIMD1
LIM domains containing 1.
   
 
 0.555
C2CD5
C2 calcium dependent domain containing 5.
      
 0.536
LIMK2
LIM domain kinase 2.
   
 
 0.531
ZNHIT1
Zinc finger HIT-type containing 1.
      
 0.526
TMEM87B
Transmembrane protein 87B.
      
 0.524
ACER1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
      
 0.523
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.