STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFRSF11BTumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa)    
Predicted Functional Partners:
TNFSF11
TNF superfamily member 11; Belongs to the tumor necrosis factor family.
   
 0.997
TGFB2
Transforming growth factor beta; Belongs to the TGF-beta family.
   
  
 0.735
TNFSF10
Tumor necrosis factor ligand superfamily member.
      
 0.666
FOSL1
FOS like 1, AP-1 transcription factor subunit.
      
 0.648
IBSP
Integrin binding sialoprotein.
   
  
 0.607
MAPK13
Mitogen-activated protein kinase.
   
  
 0.590
IFNGR2
Uncharacterized protein.
   
  
 0.590
LOC487739
Uncharacterized protein.
   
  
 0.590
GRB2
Growth factor receptor bound protein 2.
   
  
 0.586
TNFSF18
TNF superfamily member 18.
   
 
 0.585
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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