STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP8Uncharacterized protein. (627 aa)    
Predicted Functional Partners:
SH3GL1
SH3 domain containing GRB2 like 1, endophilin A2.
    
 
 0.770
SH3GL3
SH3 domain containing GRB2 like 3, endophilin A3.
    
 
 0.722
SH3GL2
SH3 domain containing GRB2 like 2, endophilin A1.
    
 
 0.586
ENSCAFP00000056396
BAR domain-containing protein.
    
 
 0.586
PRR5
Proline rich 5.
 
 
  
 0.545
ARHGAP1
Cdc42 GTPase-activating protein.
   
 
 0.499
ARHGAP22
Rho GTPase activating protein 22.
      
 0.471
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.