RSPH4A protein (Canis lupus familiaris) - STRING interaction network

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Score

RSPH4A

Radial spoke head component 4A. (719 aa)

Predicted Functional Partners:

RSPH9

0.990

RSPH3

0.979

RSPH1

0.978

DNAI1

0.935

DNAI2

0.925

CCDC65

0.902

GAA

0.899

CCDC39

0.889

NME8

0.883

ZMYND10

0.870

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC39	CCDC65	ENSCAFP00000062401	ENSCAFP00000012948	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Coiled-coil domain containing 65.	0.955
CCDC39	DNAI1	ENSCAFP00000062401	ENSCAFP00000002833	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Dynein axonemal intermediate chain 1.	0.944
CCDC39	DNAI2	ENSCAFP00000062401	ENSCAFP00000006770	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Dynein axonemal intermediate chain 2.	0.950
CCDC39	GAA	ENSCAFP00000062401	ENSCAFP00000008338	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Glucosidase alpha, acid.	0.985
CCDC39	NME8	ENSCAFP00000062401	ENSCAFP00000037304	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	NME/NM23 family member 8.	0.811
CCDC39	RSPH1	ENSCAFP00000062401	ENSCAFP00000048813	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Radial spoke head 1 homolog.	0.921
CCDC39	RSPH3	ENSCAFP00000062401	ENSCAFP00000000941	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Radial spoke head 3.	0.856
CCDC39	RSPH4A	ENSCAFP00000062401	ENSCAFP00000001279	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Radial spoke head component 4A.	0.889
CCDC39	RSPH9	ENSCAFP00000062401	ENSCAFP00000033809	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Radial spoke head 9 homolog.	0.923
CCDC39	ZMYND10	ENSCAFP00000062401	ENSCAFP00000015621	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family.	0.770
CCDC65	CCDC39	ENSCAFP00000012948	ENSCAFP00000062401	Coiled-coil domain containing 65.	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	0.955
CCDC65	DNAI1	ENSCAFP00000012948	ENSCAFP00000002833	Coiled-coil domain containing 65.	Dynein axonemal intermediate chain 1.	0.901
CCDC65	DNAI2	ENSCAFP00000012948	ENSCAFP00000006770	Coiled-coil domain containing 65.	Dynein axonemal intermediate chain 2.	0.960
CCDC65	GAA	ENSCAFP00000012948	ENSCAFP00000008338	Coiled-coil domain containing 65.	Glucosidase alpha, acid.	0.942
CCDC65	NME8	ENSCAFP00000012948	ENSCAFP00000037304	Coiled-coil domain containing 65.	NME/NM23 family member 8.	0.913
CCDC65	RSPH1	ENSCAFP00000012948	ENSCAFP00000048813	Coiled-coil domain containing 65.	Radial spoke head 1 homolog.	0.936
CCDC65	RSPH3	ENSCAFP00000012948	ENSCAFP00000000941	Coiled-coil domain containing 65.	Radial spoke head 3.	0.799
CCDC65	RSPH4A	ENSCAFP00000012948	ENSCAFP00000001279	Coiled-coil domain containing 65.	Radial spoke head component 4A.	0.902
CCDC65	RSPH9	ENSCAFP00000012948	ENSCAFP00000033809	Coiled-coil domain containing 65.	Radial spoke head 9 homolog.	0.922
CCDC65	ZMYND10	ENSCAFP00000012948	ENSCAFP00000015621	Coiled-coil domain containing 65.	Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family.	0.847