DLA-DOA protein (Canis lupus familiaris) - STRING interaction network

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Score

DLA-DOA

MHC class II antigen DO alpha; Belongs to the MHC class II family. (250 aa)

Predicted Functional Partners:

DLA-DMA

0.994

HLA-DQB2

0.971

DLA-DRA

0.960

J9NSQ1_CANLF

0.912

CD4

0.823

F1PSQ5_CANLF

0.822

HLA-DQB1

0.734

RPS14

0.734

J9NZE6_CANLF

0.734

J9P2Z6_CANLF

0.734

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD4	DLA-DMA	ENSCAFP00000063394	ENSCAFP00000001218	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	MHC class II antigen DM alpha; Belongs to the MHC class II family.	0.861
CD4	DLA-DOA	ENSCAFP00000063394	ENSCAFP00000001280	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	MHC class II antigen DO alpha; Belongs to the MHC class II family.	0.823
CD4	DLA-DRA	ENSCAFP00000063394	ENSCAFP00000045482	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.978
CD4	F1PSQ5_CANLF	ENSCAFP00000063394	ENSCAFP00000001282	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Uncharacterized protein.	0.885
CD4	HLA-DQB1	ENSCAFP00000063394	ENSCAFP00000001171	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Major histocompatibility complex, class II, DQ beta 2.	0.879
CD4	HLA-DQB2	ENSCAFP00000063394	ENSCAFP00000001156	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Major histocompatibility complex, class II, DQ beta 1.	0.820
DLA-DMA	CD4	ENSCAFP00000001218	ENSCAFP00000063394	MHC class II antigen DM alpha; Belongs to the MHC class II family.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.861
DLA-DMA	DLA-DOA	ENSCAFP00000001218	ENSCAFP00000001280	MHC class II antigen DM alpha; Belongs to the MHC class II family.	MHC class II antigen DO alpha; Belongs to the MHC class II family.	0.994
DLA-DMA	DLA-DRA	ENSCAFP00000001218	ENSCAFP00000045482	MHC class II antigen DM alpha; Belongs to the MHC class II family.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.999
DLA-DMA	F1PSQ5_CANLF	ENSCAFP00000001218	ENSCAFP00000001282	MHC class II antigen DM alpha; Belongs to the MHC class II family.	Uncharacterized protein.	0.968
DLA-DMA	HLA-DQB1	ENSCAFP00000001218	ENSCAFP00000001171	MHC class II antigen DM alpha; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DQ beta 2.	0.982
DLA-DMA	HLA-DQB2	ENSCAFP00000001218	ENSCAFP00000001156	MHC class II antigen DM alpha; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DQ beta 1.	0.992
DLA-DMA	J9NSQ1_CANLF	ENSCAFP00000001218	ENSCAFP00000040591	MHC class II antigen DM alpha; Belongs to the MHC class II family.	Ig-like domain-containing protein.	0.909
DLA-DMA	J9NZE6_CANLF	ENSCAFP00000001218	ENSCAFP00000038666	MHC class II antigen DM alpha; Belongs to the MHC class II family.	Uncharacterized protein.	0.789
DLA-DMA	J9P2Z6_CANLF	ENSCAFP00000001218	ENSCAFP00000039925	MHC class II antigen DM alpha; Belongs to the MHC class II family.	Uncharacterized protein.	0.789
DLA-DMA	RPS14	ENSCAFP00000001218	ENSCAFP00000026742	MHC class II antigen DM alpha; Belongs to the MHC class II family.	Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family.	0.789
DLA-DOA	CD4	ENSCAFP00000001280	ENSCAFP00000063394	MHC class II antigen DO alpha; Belongs to the MHC class II family.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.823
DLA-DOA	DLA-DMA	ENSCAFP00000001280	ENSCAFP00000001218	MHC class II antigen DO alpha; Belongs to the MHC class II family.	MHC class II antigen DM alpha; Belongs to the MHC class II family.	0.994
DLA-DOA	DLA-DRA	ENSCAFP00000001280	ENSCAFP00000045482	MHC class II antigen DO alpha; Belongs to the MHC class II family.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.960
DLA-DOA	F1PSQ5_CANLF	ENSCAFP00000001280	ENSCAFP00000001282	MHC class II antigen DO alpha; Belongs to the MHC class II family.	Uncharacterized protein.	0.822