STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SULT4A1Sulfotransferase; Belongs to the sulfotransferase 1 family. (390 aa)    
Predicted Functional Partners:
CNOT9
CCR4-NOT transcription complex subunit 9.
      
 0.741
IFIH1
Potassium voltage-gated channel subfamily H member 7.
   
  
 0.701
SULT1C2
Sulfotransferase; Belongs to the sulfotransferase 1 family.
  
 
0.700
SULT1A1
Sulfotransferase 1A1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.
  
 
0.688
KMT2E
Lysine methyltransferase 2E.
      
 0.677
SULT1B1
Sulfotransferase family cytosolic 1B member 1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates thyroid hormones including 3,3'-diiodothyronine, 3,5,3'-triidothyronine and 3,5'- diiodothyronine (lesser degree) and phenols such as 1-naphthol and p- nitrophenol.
  
 
0.655
SULT1C4
Sulfotransferase; Belongs to the sulfotransferase 1 family.
  
 
0.606
SERPINB10
Serpin family B member 10; Belongs to the serpin family.
      
 0.599
LOC482182
Sulfotransferase; Belongs to the sulfotransferase 1 family.
  
 
0.599
SULT6B1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
  
  
0.574
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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