F1PSQ5_CANLF protein (Canis lupus familiaris)

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Score

F1PSQ5_CANLF

Uncharacterized protein. (228 aa)

Predicted Functional Partners:

DLA-DRA

0.980

E2R820_CANLF

0.972

DLA-DQA1

0.970

CD74

0.933

DLA-DMA

0.742

J9P3Z4_CANLF

0.741

INS

0.741

CD4

0.735

ACAN

0.728

COL2A1

0.727

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAN	COL2A1	ENSCAFP00000065577	ENSCAFP00000013330	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Collagen type II alpha 1 chain.	0.953
ACAN	DLA-DRA	ENSCAFP00000065577	ENSCAFP00000045482	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.720
ACAN	F1PSQ5_CANLF	ENSCAFP00000065577	ENSCAFP00000001282	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Uncharacterized protein.	0.728
ACAN	INS	ENSCAFP00000065577	ENSCAFP00000051648	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.544
CD4	DLA-DQA1	ENSCAFP00000063394	ENSCAFP00000001164	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.682
CD4	DLA-DRA	ENSCAFP00000063394	ENSCAFP00000045482	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.984
CD4	E2R820_CANLF	ENSCAFP00000063394	ENSCAFP00000034736	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	DUF1968 domain-containing protein.	0.599
CD4	F1PSQ5_CANLF	ENSCAFP00000063394	ENSCAFP00000001282	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Uncharacterized protein.	0.735
CD4	INS	ENSCAFP00000063394	ENSCAFP00000051648	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.656
CD74	DLA-DMA	ENSCAFP00000045678	ENSCAFP00000001218	CD74 molecule.	MHC class II antigen DM alpha; Belongs to the MHC class II family.	0.782
CD74	DLA-DQA1	ENSCAFP00000045678	ENSCAFP00000001164	CD74 molecule.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.959
CD74	DLA-DRA	ENSCAFP00000045678	ENSCAFP00000045482	CD74 molecule.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.987
CD74	F1PSQ5_CANLF	ENSCAFP00000045678	ENSCAFP00000001282	CD74 molecule.	Uncharacterized protein.	0.933
COL2A1	ACAN	ENSCAFP00000013330	ENSCAFP00000065577	Collagen type II alpha 1 chain.	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	0.953
COL2A1	DLA-DRA	ENSCAFP00000013330	ENSCAFP00000045482	Collagen type II alpha 1 chain.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.719
COL2A1	F1PSQ5_CANLF	ENSCAFP00000013330	ENSCAFP00000001282	Collagen type II alpha 1 chain.	Uncharacterized protein.	0.727
DLA-DMA	CD74	ENSCAFP00000001218	ENSCAFP00000045678	MHC class II antigen DM alpha; Belongs to the MHC class II family.	CD74 molecule.	0.782
DLA-DMA	DLA-DQA1	ENSCAFP00000001218	ENSCAFP00000001164	MHC class II antigen DM alpha; Belongs to the MHC class II family.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.613
DLA-DMA	DLA-DRA	ENSCAFP00000001218	ENSCAFP00000045482	MHC class II antigen DM alpha; Belongs to the MHC class II family.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.992
DLA-DMA	F1PSQ5_CANLF	ENSCAFP00000001218	ENSCAFP00000001282	MHC class II antigen DM alpha; Belongs to the MHC class II family.	Uncharacterized protein.	0.742