STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCUBE1Signal peptide, CUB domain and EGF like domain containing 1. (1001 aa)    
Predicted Functional Partners:
GCC2
GRIP and coiled-coil domain containing 2.
    
 
 0.812
SCUBE3
Signal peptide, CUB domain and EGF like domain containing 3.
  
  
0.757
MPDZ
Multiple PDZ domain crumbs cell polarity complex component.
   
 
 0.675
CDON
Cell adhesion associated, oncogene regulated.
    
 
 0.592
SIAH1
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
      
 0.558
SUGCT
Succinyl-CoA:glutarate-CoA transferase.
    
 
 0.520
ARID4B
AT-rich interaction domain 4B.
    
 
 0.514
EHMT1
Euchromatic histone lysine methyltransferase 1.
    
 
 0.502
CHRDL2
Chordin like 2.
      
 0.501
CPXM1
Carboxypeptidase X, M14 family member 1.
      
 0.489
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.