STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPNA5Importin subunit alpha; Functions in nuclear protein import. (539 aa)    
Predicted Functional Partners:
KPNB1
Karyopherin subunit beta 1.
   
 
 0.944
DCAF1
DDB1 and CUL4 associated factor 1.
      
 0.795
RANBP2
RAN binding protein 2.
   
 
 0.613
CSE1L
Chromosome segregation 1 like.
   
 
 0.596
NUP50
Nucleoporin 50.
   
 
 0.593
EXO1
Exonuclease 1.
   
 
 0.550
TNPO2
Transportin 2.
   
 
 0.545
NCBP1
Nuclear cap binding protein subunit 1.
   
 
 0.542
NUP153
Nucleoporin 153.
   
 
 0.538
PPIL4
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
   
  
 0.534
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.