STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SOWAHASosondowah ankyrin repeat domain family member A. (570 aa)    
Predicted Functional Partners:
FAM189A2
Family with sequence similarity 189 member A2.
    
 
 0.884
DNASE2B
Deoxyribonuclease 2 beta.
      
 0.818
BLK
Tyrosine-protein kinase.
    
 
 0.698
C9orf116
Chromosome 9 open reading frame 116.
    
 
 0.693
GNS
N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.
    
 0.687
KRT80
Keratin 80; Belongs to the intermediate filament family.
      
 0.671
CORIN
Corin, serine peptidase.
    
 
 0.623
COL4A3
Collagen type IV alpha 3 chain.
    
 
 0.545
STAR
Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
      
 0.520
DIAPH1
Diaphanous related formin 1.
    
 
 0.505
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.