STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ROS1Tyrosine-protein kinase receptor. (2343 aa)    
Predicted Functional Partners:
EML4
EMAP like 4.
   
 
 0.841
KRAS
KRAS proto-oncogene, GTPase.
   
 
 0.723
GRB2
Growth factor receptor bound protein 2.
    
 
 0.629
ENSCAFP00000057906
Uncharacterized protein.
    
 
 0.617
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 
 0.596
CRYBG1
Crystallin beta-gamma domain containing 1; Belongs to the beta/gamma-crystallin family.
  
 
 
 0.583
ALK
Tyrosine-protein kinase receptor.
   
  
0.578
CEP85L
Centrosomal protein 85 like.
    
 
 0.570
SLC34A2
Solute carrier family 34 member 2.
   
 
 0.557
LRIG3
Leucine rich repeats and immunoglobulin like domains 3.
    
 
 0.518
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.