STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZHX2Zinc fingers and homeoboxes 2. (838 aa)    
Predicted Functional Partners:
RABGEF1
RAB guanine nucleotide exchange factor 1.
   
 
 0.876
TBC1D31
TBC1 domain family member 31.
 
  
 
 0.872
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
 
 0.852
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 
 0.851
POLN
DNA polymerase nu.
   
  
 0.658
RNF139
Ring finger protein 139.
      
 0.647
RBSN
Rabenosyn, RAB effector.
   
 
 0.604
ZBTB4
Zinc finger and BTB domain containing 4.
   
 
 0.601
TATDN1
TatD DNase domain containing 1.
      
 0.598
TNK1
Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
      
 0.587
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.