STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB22Zinc finger and BTB domain-containing protein 22; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (593 aa)    
Predicted Functional Partners:
DAXX
Death domain-associated protein 6; Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Inhibits transcriptional activation of PAX3 and ETS1 throu [...]
 
  
 
 0.598
MAFG
MAF bZIP transcription factor G.
    
 
 0.524
KIF25
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 
 0.498
KIFC3
Kinesin family member C3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 
 0.498
KIFC2
Kinesin family member C2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 
 0.476
RGL2
Ral guanine nucleotide dissociation stimulator-like 2; Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro (By similarity).
      
 0.476
UHRF1BP1
UHRF1 binding protein 1.
      
 0.469
PRPF39
Pre-mRNA processing factor 39.
      
 0.468
DHX35
DEAH-box helicase 35.
   
 0.433
TAPBP
Tapasin; Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
    
 
 0.415
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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