STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NAGAAlpha-galactosidase. (411 aa)    
Predicted Functional Partners:
HEXA
Beta-hexosaminidase.
   
 
 0.941
B3GALT5
Hexosyltransferase.
   
 
 0.927
HEXB
Hexosaminidase subunit beta.
   
 
 0.926
GBA3
Glucosylceramidase beta 3; Belongs to the glycosyl hydrolase 1 family.
      
 0.905
GBGT1
Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1; Catalyzes the formation of Forssman glycolipid via the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to GalNAcb-1,3Gala-1,4Galb-1,4GlcCer (Gb4Cer). Forssman glycolipid (also called Forssman antigen; FG) probably serves for adherence of some pathogens such as E.coli uropathogenic strains; Belongs to the glycosyltransferase 6 family.
   
 
 0.901
ASL
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
   
  
 0.753
CCNJ
Cyclin J; Belongs to the cyclin family.
      
 0.703
RP2
RP2 activator of ARL3 GTPase.
   
  
 0.638
LOC479649
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
      
 0.628
CTRB2
Chymotrypsin 2 chain A; Belongs to the peptidase S1 family.
      
 0.627
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.