STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFRSF13CTNF receptor superfamily member 13C. (286 aa)    
Predicted Functional Partners:
TNFSF13B
Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family.
    
 0.997
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.987
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.941
TRAF5
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.907
TRAF1
TNF receptor associated factor 1.
    
 0.859
TNFSF12
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
     
 0.781
CD79B
CD79b molecule.
   
  
 0.776
LTBR
Lymphotoxin beta receptor.
   
 
 0.759
TNFRSF13B
TNF receptor superfamily member 13B.
   
  
 0.758
CD40LG
CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...]
     
 0.679
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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