STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL38Kelch like family member 38. (594 aa)    
Predicted Functional Partners:
NEURL1B
Neuralized E3 ubiquitin protein ligase 1B.
      
 0.659
USP28
Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family.
   
 
 0.655
CUL3
Cullin 3; Belongs to the cullin family.
    
 
 0.614
DLEC1
DLEC1 cilia and flagella associated protein.
    
 
 0.608
TRIM55
Tripartite motif containing 55.
   
 
 0.603
CHD6
Chromodomain helicase DNA binding protein 6.
    
 
 0.602
CCDC141
Coiled-coil domain containing 141.
   
 
 0.596
UBR3
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
  
 0.566
KLHL9-2
Uncharacterized protein.
  
   0.554
WWP1
E3 ubiquitin-protein ligase.
   
 
 0.532
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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