STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYNGAP1Synaptic Ras GTPase activating protein 1. (612 aa)    
Predicted Functional Partners:
RRAS2
RAS related 2.
    
 0.760
RRAS
RAS related.
    
 0.750
MRAS
Muscle RAS oncogene homolog.
    
 0.719
NRAS
Uncharacterized protein.
    
 0.719
HRAS
Uncharacterized protein.
    
 0.719
DLG3-2
SH3 domain-containing protein.
    
 
 0.690
DLG3
Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.
    
 
 0.690
SLITRK2
SLIT and NTRK like family member 2.
    
 
 0.677
IQSEC2
IQ motif and Sec7 domain 2.
    
 
 0.661
CDC42SE1
CDC42 small effector 1.
      
 0.637
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.