SREBF2 protein (Canis lupus familiaris) - STRING interaction network

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Score

SREBF2

Sterol regulatory element binding transcription factor 2. (1131 aa)

Predicted Functional Partners:

SCAP

0.844

LDLR

0.820

CREBBP

0.815

KPNB1

0.805

LPIN1

0.790

PPARGC1B

0.789

MED15

0.781

NPC1

0.775

HMGCR

0.753

EP300

0.692

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CREBBP	EP300	ENSCAFP00000036447	ENSCAFP00000001585	CREB binding protein.	E1A binding protein p300.	0.999
CREBBP	PPARGC1B	ENSCAFP00000036447	ENSCAFP00000052080	CREB binding protein.	PPARG coactivator 1 beta.	0.532
CREBBP	SREBF2	ENSCAFP00000036447	ENSCAFP00000001434	CREB binding protein.	Sterol regulatory element binding transcription factor 2.	0.815
EP300	CREBBP	ENSCAFP00000001585	ENSCAFP00000036447	E1A binding protein p300.	CREB binding protein.	0.999
EP300	SREBF2	ENSCAFP00000001585	ENSCAFP00000001434	E1A binding protein p300.	Sterol regulatory element binding transcription factor 2.	0.692
HMGCR	LDLR	ENSCAFP00000061137	ENSCAFP00000043416	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Low density lipoprotein receptor.	0.862
HMGCR	NPC1	ENSCAFP00000061137	ENSCAFP00000057176	3-hydroxy-3-methylglutaryl coenzyme A reductase.	NPC intracellular cholesterol transporter 1.	0.615
HMGCR	SCAP	ENSCAFP00000061137	ENSCAFP00000019461	3-hydroxy-3-methylglutaryl coenzyme A reductase.	SREBF chaperone.	0.427
HMGCR	SREBF2	ENSCAFP00000061137	ENSCAFP00000001434	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Sterol regulatory element binding transcription factor 2.	0.753
KPNB1	SREBF2	ENSCAFP00000044873	ENSCAFP00000001434	Karyopherin subunit beta 1.	Sterol regulatory element binding transcription factor 2.	0.805
LDLR	HMGCR	ENSCAFP00000043416	ENSCAFP00000061137	Low density lipoprotein receptor.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.862
LDLR	NPC1	ENSCAFP00000043416	ENSCAFP00000057176	Low density lipoprotein receptor.	NPC intracellular cholesterol transporter 1.	0.558
LDLR	SREBF2	ENSCAFP00000043416	ENSCAFP00000001434	Low density lipoprotein receptor.	Sterol regulatory element binding transcription factor 2.	0.820
LPIN1	SREBF2	ENSCAFP00000045724	ENSCAFP00000001434	Lipin 1.	Sterol regulatory element binding transcription factor 2.	0.790
MED15	SREBF2	ENSCAFP00000022008	ENSCAFP00000001434	Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Sterol regulatory element binding transcription factor 2.	0.781
NPC1	HMGCR	ENSCAFP00000057176	ENSCAFP00000061137	NPC intracellular cholesterol transporter 1.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.615
NPC1	LDLR	ENSCAFP00000057176	ENSCAFP00000043416	NPC intracellular cholesterol transporter 1.	Low density lipoprotein receptor.	0.558
NPC1	SREBF2	ENSCAFP00000057176	ENSCAFP00000001434	NPC intracellular cholesterol transporter 1.	Sterol regulatory element binding transcription factor 2.	0.775
PPARGC1B	CREBBP	ENSCAFP00000052080	ENSCAFP00000036447	PPARG coactivator 1 beta.	CREB binding protein.	0.532
PPARGC1B	SREBF2	ENSCAFP00000052080	ENSCAFP00000001434	PPARG coactivator 1 beta.	Sterol regulatory element binding transcription factor 2.	0.789