MEI1 protein (Canis lupus familiaris) - STRING interaction network

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Predicted Interactions

gene neighborhood

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[Homology]

Score

MEI1

Meiotic double-stranded break formation protein 1. (1272 aa)

Predicted Functional Partners:

REC114

0.950

ANKRD31

0.924

SYCE1

0.850

RAE1

0.815

HORMAD1

0.815

SYCP1

0.785

REC8

0.747

PIWIL1

0.680

MEIOC

0.678

M1AP

0.677

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD31	HORMAD1	ENSCAFP00000042196	ENSCAFP00000017772	Ankyrin repeat domain 31.	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	0.691
ANKRD31	MEI1	ENSCAFP00000042196	ENSCAFP00000001457	Ankyrin repeat domain 31.	Meiotic double-stranded break formation protein 1.	0.924
ANKRD31	RAE1	ENSCAFP00000042196	ENSCAFP00000017710	Ankyrin repeat domain 31.	SPO11 initiator of meiotic double stranded breaks.	0.623
ANKRD31	REC114	ENSCAFP00000042196	ENSCAFP00000026260	Ankyrin repeat domain 31.	REC114 meiotic recombination protein.	0.985
ANKRD31	REC8	ENSCAFP00000042196	ENSCAFP00000017702	Ankyrin repeat domain 31.	REC8 meiotic recombination protein.	0.419
ANKRD31	SYCE1	ENSCAFP00000042196	ENSCAFP00000033815	Ankyrin repeat domain 31.	Synaptonemal complex central element protein 1.	0.741
ANKRD31	SYCP1	ENSCAFP00000042196	ENSCAFP00000037843	Ankyrin repeat domain 31.	Synaptonemal complex protein 1.	0.686
HORMAD1	ANKRD31	ENSCAFP00000017772	ENSCAFP00000042196	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Ankyrin repeat domain 31.	0.691
HORMAD1	M1AP	ENSCAFP00000017772	ENSCAFP00000041979	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Meiosis 1 associated protein.	0.440
HORMAD1	MEI1	ENSCAFP00000017772	ENSCAFP00000001457	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Meiotic double-stranded break formation protein 1.	0.815
HORMAD1	MEIOC	ENSCAFP00000017772	ENSCAFP00000060593	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Meiosis specific with coiled-coil domain.	0.625
HORMAD1	RAE1	ENSCAFP00000017772	ENSCAFP00000017710	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	SPO11 initiator of meiotic double stranded breaks.	0.958
HORMAD1	REC114	ENSCAFP00000017772	ENSCAFP00000026260	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	REC114 meiotic recombination protein.	0.735
HORMAD1	REC8	ENSCAFP00000017772	ENSCAFP00000017702	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	REC8 meiotic recombination protein.	0.874
HORMAD1	SYCE1	ENSCAFP00000017772	ENSCAFP00000033815	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Synaptonemal complex central element protein 1.	0.874
HORMAD1	SYCP1	ENSCAFP00000017772	ENSCAFP00000037843	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	Synaptonemal complex protein 1.	0.922
M1AP	HORMAD1	ENSCAFP00000041979	ENSCAFP00000017772	Meiosis 1 associated protein.	HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...]	0.440
M1AP	MEI1	ENSCAFP00000041979	ENSCAFP00000001457	Meiosis 1 associated protein.	Meiotic double-stranded break formation protein 1.	0.677
M1AP	MEIOC	ENSCAFP00000041979	ENSCAFP00000060593	Meiosis 1 associated protein.	Meiosis specific with coiled-coil domain.	0.776
MEI1	ANKRD31	ENSCAFP00000001457	ENSCAFP00000042196	Meiotic double-stranded break formation protein 1.	Ankyrin repeat domain 31.	0.924