STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TATDN1TatD DNase domain containing 1. (347 aa)    
Predicted Functional Partners:
RNF139
Ring finger protein 139.
   
  
 0.798
EIF3E
Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]
   
  
 0.788
ZNF74
Zinc finger protein 74.
      
 0.743
MTSS1
MTSS I-BAR domain containing 1.
      
 0.703
MRPL13
Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.
  
  
 0.701
KLHL22
Kelch like family member 22.
      
 0.644
PFDN5
Uncharacterized protein.
   
  
 0.627
NDUFB1
Uncharacterized protein.
      
 0.612
ZHX2
Zinc fingers and homeoboxes 2.
      
 0.601
PKHD1L1
PKHD1 like 1.
      
 0.597
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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