Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CSDC2Cold shock domain containing C2. (152 aa)    
Predicted Functional Partners:
PPP2R1B
Protein phosphatase 2 scaffold subunit Abeta.
    
   0.685
PPP2R1A
Protein phosphatase 2 scaffold subunit Aalpha.
    
   0.685
PRSS53
Serine protease 53; Belongs to the peptidase S1 family.
      
 0.568
AKNAD1
AKNA domain containing 1.
   
  
 0.567
STARD9
StAR related lipid transfer domain containing 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 
 0.495
SSRP1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
  
 0.480
LETMD1
LETM1 domain containing 1.
      
 0.471
CIP2A
Cell proliferation regulating inhibitor of protein phosphatase 2A.
      
 0.466
PJA2
Praja ring finger ubiquitin ligase 2.
      
 0.464
DDX6
DEAD-box helicase 6; Belongs to the DEAD box helicase family.
   
 
 0.460
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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