STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TXNDC15Thioredoxin domain containing 15. (348 aa)    
Predicted Functional Partners:
TTC23
Tetratricopeptide repeat domain 23.
      
 0.650
MARCHF6
Membrane associated ring-CH-type finger 6.
    
   0.615
PIGN
Phosphatidylinositol glycan anchor biosynthesis class N.
    
   0.582
CAMLG
Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.
   
  
 0.563
CATSPER3
Cation channel sperm associated 3.
      
 0.551
TMX1
Thioredoxin related transmembrane protein 1.
      
 0.529
SLC25A48
Solute carrier family 25 member 48; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.519
FAM92A
Family with sequence similarity 92 member A.
      
 0.505
INTS6
Integrator complex subunit 6.
      
 0.477
LRRCC1
Leucine rich repeat and coiled-coil centrosomal protein 1.
      
 0.475
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.