STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRIB1Protein kinase domain-containing protein. (372 aa)    
Predicted Functional Partners:
COP1
COP1 E3 ubiquitin ligase.
    
 
 0.850
STK40
Serine/threonine kinase 40.
   
 
0.668
DET1
DET1 partner of COP1 E3 ubiquitin ligase.
    
 
 0.632
CEBPE
CCAAT enhancer binding protein epsilon.
   
 
 0.615
CD72
CD72 molecule.
    
 
 0.614
ARRDC2
Arrestin domain containing 2.
   
 
 0.602
RUBCNL
Rubicon like autophagy enhancer.
      
 0.570
RABGAP1L
RAB GTPase activating protein 1 like.
    
 
 0.560
TRIB2
Tribbles homolog 2; Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.
  
 
 
0.553
RIBC2
RIB43A domain with coiled-coils 2.
   
 0.543
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.