STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THEMISThymocyte selection associated. (653 aa)    
Predicted Functional Partners:
TIFA
TRAF interacting protein with forkhead associated domain.
      
 0.857
GRB2
Growth factor receptor bound protein 2.
   
 
 0.702
SIT1
Signaling threshold regulating transmembrane adaptor 1.
   
  
 0.689
ITK
Tyrosine-protein kinase.
   
 
 0.661
RGS13
Regulator of G protein signaling 13.
   
  
 0.622
GRAP2
GRB2 related adaptor protein 2.
   
 
 0.579
ARL10
ADP ribosylation factor like GTPase 10.
   
  
 0.564
F3
Coagulation factor III, tissue factor.
      
 0.560
PTPRK
Protein tyrosine phosphatase receptor type K.
   
 
 0.543
ZNF831
Zinc finger protein 831.
   
  
 0.538
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.