STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSDMCGasdermin C. (506 aa)    
Predicted Functional Partners:
GSDMB
Gasdermin domain-containing protein.
      
 0.923
GSDME
Gasdermin E.
      
 0.828
PJVK
Pejvakin.
      
 0.796
MYPOP
Myb related transcription factor, partner of profilin.
      
 0.605
SCAF11
SR-related CTD associated factor 11.
      
 0.563
CASP6
Caspase 6; Belongs to the peptidase C14A family.
   
  
 0.545
PRDM6
PR/SET domain 6.
      
 0.529
SRRT
Serrate, RNA effector molecule.
      
 0.519
KCNG2
Ion_trans_2 domain-containing protein.
      
 0.517
NLRP1
NLR family pyrin domain containing 1.
      
 0.514
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.