STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1132 aa)    
Predicted Functional Partners:
ARF6
ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
    
 0.979
ASAP3
Uncharacterized protein.
    
  0.973
SH3KBP1
SH3 domain containing kinase binding protein 1.
   
 
0.944
CTTN
Cortactin.
   
 
 0.938
GRB2
Growth factor receptor bound protein 2.
    
 
 0.903
ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2.
     
  0.881
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 
 0.879
CRK
CRK proto-oncogene, adaptor protein.
    
 
 0.865
PACSIN2
Protein kinase C and casein kinase substrate in neurons 2.
    
 
 0.829
APC
APC regulator of WNT signaling pathway.
    
   0.791
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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