LRRC6 protein (Canis lupus familiaris) - STRING interaction network

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Score

LRRC6

Leucine rich repeat containing 6. (469 aa)

Predicted Functional Partners:

ZMYND10

0.929

CCDC103

0.895

DNAAF5

0.871

DNAI2

0.870

SPAG1

0.866

DNALI1

0.839

DNAI1

0.835

CCDC39

0.832

DNAAF3

0.823

CCDC65

0.819

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC103	CCDC39	ENSCAFP00000020601	ENSCAFP00000062401	Coiled-coil domain containing 103.	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	0.868
CCDC103	CCDC65	ENSCAFP00000020601	ENSCAFP00000012948	Coiled-coil domain containing 103.	Coiled-coil domain containing 65.	0.752
CCDC103	DNAAF3	ENSCAFP00000020601	ENSCAFP00000003802	Coiled-coil domain containing 103.	Dynein axonemal assembly factor 3.	0.816
CCDC103	DNAAF5	ENSCAFP00000020601	ENSCAFP00000055658	Coiled-coil domain containing 103.	Dynein axonemal assembly factor 5.	0.790
CCDC103	DNAI1	ENSCAFP00000020601	ENSCAFP00000002833	Coiled-coil domain containing 103.	Dynein axonemal intermediate chain 1.	0.878
CCDC103	DNAI2	ENSCAFP00000020601	ENSCAFP00000006770	Coiled-coil domain containing 103.	Dynein axonemal intermediate chain 2.	0.937
CCDC103	DNALI1	ENSCAFP00000020601	ENSCAFP00000043556	Coiled-coil domain containing 103.	Dynein axonemal light intermediate chain 1.	0.557
CCDC103	LRRC6	ENSCAFP00000020601	ENSCAFP00000001566	Coiled-coil domain containing 103.	Leucine rich repeat containing 6.	0.895
CCDC103	SPAG1	ENSCAFP00000020601	ENSCAFP00000000777	Coiled-coil domain containing 103.	Uncharacterized protein.	0.770
CCDC103	ZMYND10	ENSCAFP00000020601	ENSCAFP00000015621	Coiled-coil domain containing 103.	Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family.	0.855
CCDC39	CCDC103	ENSCAFP00000062401	ENSCAFP00000020601	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Coiled-coil domain containing 103.	0.868
CCDC39	CCDC65	ENSCAFP00000062401	ENSCAFP00000012948	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Coiled-coil domain containing 65.	0.955
CCDC39	DNAAF3	ENSCAFP00000062401	ENSCAFP00000003802	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Dynein axonemal assembly factor 3.	0.702
CCDC39	DNAAF5	ENSCAFP00000062401	ENSCAFP00000055658	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Dynein axonemal assembly factor 5.	0.673
CCDC39	DNAI1	ENSCAFP00000062401	ENSCAFP00000002833	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Dynein axonemal intermediate chain 1.	0.944
CCDC39	DNAI2	ENSCAFP00000062401	ENSCAFP00000006770	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Dynein axonemal intermediate chain 2.	0.950
CCDC39	DNALI1	ENSCAFP00000062401	ENSCAFP00000043556	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Dynein axonemal light intermediate chain 1.	0.942
CCDC39	LRRC6	ENSCAFP00000062401	ENSCAFP00000001566	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Leucine rich repeat containing 6.	0.832
CCDC39	SPAG1	ENSCAFP00000062401	ENSCAFP00000000777	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Uncharacterized protein.	0.718
CCDC39	ZMYND10	ENSCAFP00000062401	ENSCAFP00000015621	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.	Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family.	0.770