STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRC6Leucine rich repeat containing 6. (469 aa)    
Predicted Functional Partners:
CCDC103
Coiled-coil domain containing 103.
   
 
 0.923
DNAAF5
Dynein axonemal assembly factor 5.
   
  
 0.920
DNAAF4
Dynein axonemal assembly factor 4.
   
 
 0.909
DNAH11
Dynein axonemal heavy chain 11.
   
 
 0.888
DNAI2
Dynein axonemal intermediate chain 2.
    
 
 0.862
CCDC65
Coiled-coil domain containing 65.
   
  
 0.842
DNAAF3
Dynein axonemal assembly factor 3.
      
 0.808
ZMYND10
Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family.
   
 
 0.806
SPAG1
Uncharacterized protein.
   
 
 0.802
PIH1D3
PIH1 domain containing 3.
   
  
 0.796
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.