STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAMD3Sterile alpha motif domain containing 3. (518 aa)    
Predicted Functional Partners:
PSMD3
Proteasome 26S subunit, non-ATPase 3.
      
 0.599
SMAD3
Mothers against decapentaplegic homolog.
      
 0.533
RNF157
Ring finger protein 157.
      
 0.532
UNC45B
Unc-45 myosin chaperone B.
    
 
 0.487
DNAAF4
Dynein axonemal assembly factor 4.
      
 0.476
TMEM79
Transmembrane protein 79.
      
 0.454
EOMES
Eomesodermin.
   
  
 0.439
KLRD1
Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
   
   0.438
ANO1
Anoctamin.
      
 0.426
GZMA
Granzyme A; Belongs to the peptidase S1 family.
   
 
 0.413
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.