STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL3Kelch like family member 3. (588 aa)    
Predicted Functional Partners:
AOC3
Amine oxidase copper containing 3.
    
 
 0.988
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.975
WNK1
WNK lysine deficient protein kinase 1.
    
 
 0.973
WNK3
WNK lysine deficient protein kinase 3.
    
 
 0.885
KEAP1
Kelch like ECH associated protein 1.
    
   0.831
KLHL12
Adiponectin receptor 1.
    
   0.819
RBX1
Ring-box 1.
    
 0.815
KLHL2
Kelch like family member 2.
    
   0.809
FBXL17
F-box and leucine rich repeat protein 17.
    
 0.723
KPNA7
Importin subunit alpha; Functions in nuclear protein import.
    
 
 0.694
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.